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Kidney Transplantation: Facts and Myths

Kidney Transplantation: Facts and Myths
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By Dr. Air Cmde Gurwinder Singh Sethi in Nephrology

Jan 17, 2025

Kidney transplantation is a life-saving procedure for individuals with end-stage renal disease (ESRD), offering them the opportunity to live a longer, healthier life. For those considering kidney transplant surgery, understanding the facts and dispelling common myths is crucial. This blog delves into essential information surrounding kidney transplants, helping you make informed decisions.

What is a Kidney Transplant?

A kidney transplant involves surgically placing a healthy kidney from a donor into a patient whose kidneys have permanently failed. The transplant can be from a living donor, typically a relative or friend, or from a deceased donor. The primary goal of this procedure is to restore kidney function, allowing the recipient to live without the need for dialysis.

When is a Kidney Transplant Needed?

Kidney transplants are typically considered when a person’s kidneys have permanently stopped functioning, leading to end-stage renal disease (ESRD). This condition is classified as chronic kidney disease (CKD) stage 5. At this stage, the kidneys have irreversible damage, and their function is less than 15% of normal levels. Patients with ESRD face the choice of long-term dialysis or kidney transplantation. Transplantation is generally the preferred option as it offers better long-term outcomes and a better quality of life.

Ideal Timing for Kidney Transplantation

International medical guidelines suggest that patients should begin the transplant evaluation process when kidney function drops to below 20%. However, kidney transplantation performed before starting dialysis (known as "preemptive transplantation") is ideal. Studies have shown that preemptive transplants lead to better outcomes, with patients having improved kidney function and a reduced risk of complications compared to those who begin dialysis before receiving a transplant.

Kidney Transplant vs. Dialysis: Which is Better?

For individuals with ESRD, kidney transplantation offers several advantages over staying on dialysis. People who undergo a kidney transplant tend to live longer and experience a better quality of life. One key benefit is the avoidance of the various side effects that accompany dialysis, such as fatigue, restriction on food and fluid intake, and the need for regular dialysis sessions.

Additionally, transplant recipients often experience fewer lifestyle and dietary restrictions than those on dialysis. Importantly, the cost of kidney transplantation is lower in the long run compared to the ongoing expenses of dialysis, especially in cities like Delhi/NCR, where the cost of dialysis can quickly become overwhelming.

ABO Incompatible Kidney Transplantation: Is it Possible?

One common misconception about kidney transplantation is that the recipient's and donor's blood groups must match for the surgery to be successful. In reality, kidney transplants can be performed even when there is a mismatch in blood groups. This is called ABO-incompatible kidney transplantation. To facilitate this, the recipient must undergo additional treatments, such as plasmapheresis or immunoadsorption, to remove antibodies from their blood that could attack the transplanted kidney. Hospitals like Paras Hospital, Panchkula, have specialized teams trained to manage these complex cases.

Is Donating a Kidney Safe?

The thought of donating a kidney can raise concerns about the donor’s safety. While any surgery carries risks, kidney donation is generally considered safe. Research shows that the risk of developing kidney failure after donation is approximately 1 in 1000. Most kidney donors recover fully and lead normal lives after the procedure. Donors are thoroughly evaluated to ensure they are physically healthy enough to undergo surgery and live with just one kidney.

Can Diabetic Patients Receive a Kidney Transplant?

Yes, diabetic patients can undergo kidney transplantation. In fact, diabetes is one of the leading causes of kidney failure worldwide. Diabetes itself is not a contraindication for kidney transplant surgery, although additional medical management may be required to control blood sugar levels and ensure the patient is in optimal health for surgery. Kidney transplants can provide these patients with a much-needed chance at a better quality of life.

Risks of Kidney Transplantation

Like any major surgery, kidney transplantation carries certain risks. Some of the common risks include complications from anesthesia, bleeding, or infection. Following the transplant, recipients are typically placed on immunosuppressant medications to prevent the body from rejecting the new kidney. While these medications are crucial for the success of the transplant, they can increase the recipient’s susceptibility to infections, such as urinary tract infections, pneumonia, and viral infections.

Additionally, as with any major surgery, there is always a risk of organ rejection, and long-term health monitoring is essential. However, with proper care, regular check-ups, and adherence to medication regimens, the success rate of kidney transplants has significantly improved over the years.

Myths vs. Facts: Clearing the Air

Myth 1: Kidney transplant surgery is too risky.

Fact: Kidney transplants are major surgeries, but with advances in medical technology, they are now safer than ever. The success rates for kidney transplants are high, and many people live long, healthy lives after the procedure.

Myth 2: Kidney donors face a high risk of kidney failure later in life.

Fact: The risk of kidney failure after donation is extremely low, at about 1 in 1000. Kidney donors are thoroughly assessed for their health before donating, and most experience no long-term problems.

Myth 3: A kidney transplant can only work if the blood types match.

Fact: Kidney transplants can be performed even if blood types do not match, thanks to advanced procedures like plasmapheresis. ABO-incompatible transplants are becoming more common and successful.

Conclusion

Kidney transplantation is a transformative procedure for those with kidney failure. It offers numerous benefits over dialysis, providing recipients with a better quality of life and greater freedom. However, like any major surgery, it comes with its own set of risks and challenges. By understanding the facts surrounding kidney transplantation, patients can make well-informed decisions that will lead to healthier, longer lives.

Don’t let kidney problems hold you back. At Paras Hospitals, our expert team is here to guide you through every step of your kidney care journey. Whether you’re considering a kidney transplant or need more information, we’re just a call away.

📞 Call us now at 8080808069 or visit Paras Hospitals to book an appointment. Take the first step toward a healthier, worry-free life today!

Dr. Air Cmde Gurwinder Singh Sethi
Urology - KTP
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