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Understanding Migraines: Causes, Symptoms, Treatment, and Management

Understanding Migraines: Causes, Symptoms, Treatment, and Management
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By Dr. Raja Radhika Raman in Neuro Sciences

Mar 20, 2025

A migraine attack can cause intense pain and sensitivity to light, often forcing people to halt their daily activities. Migraine is a neurological condition known for causing severe headaches and other symptoms. It’s extremely common, affecting about 1 in every 5 women and 1 in 15 men​– over one billion people worldwide. In fact, migraine is a leading cause of disability globally​. Unlike an ordinary headache, a migraine attack can be debilitating, disrupting work, school, and daily life for those who suffer from it.

Causes

Migraines arise from a complex mix of factors. Genetics play a role – migraines often run in families, suggesting an inherited predisposition. Neurological factors are also key: changes in the brainstem and its interaction with the trigeminal nerve (a major pain pathway) are thought to be involved, along with imbalances in brain chemicals like serotonin​. These changes make the brain of a migraine sufferer more sensitive to triggers. Environmental factors frequently act as triggers that set off a migraine in someone who is prone to them. Common migraine triggers include:

  • Hormonal changes (especially in women): Fluctuations in estrogen (for example, around menstrual periods, pregnancy, or menopause) can trigger migraines​. Many women notice headaches just before or during their period.
  • Stress: Emotional stress or anxiety can prompt migraine attacks​. Stress at work, school, or home is a frequently reported trigger.
  • Sensory stimuli: Bright or flickering lights, loud sounds, or strong smells (perfume, smoke, etc.) can induce migraines for some people​. For example, walking into a flashing strobe light or a room with a powerful odor might trigger pain.
  • Sleep changes: Both lack of sleep and oversleeping can provoke migraines​. Irregular sleep schedules or jet lag may also set off an attack.
  • Physical exertion: Extremely intense exercise or physical activity (and even sudden coughing or sneezing in those already prone) might trigger a migraine​.
  • Weather changes: Changes in weather or barometric pressure (such as an incoming storm or high humidity) can lead to migraines in susceptible individuals​.
  • Certain foods and drinks: Aged cheeses, processed meats (with nitrates), chocolate, red wine, and beverages with too much caffeine (or caffeine withdrawal) are well-known culprits​. Skipping meals can also trigger headaches by causing low blood sugar.
  • Dehydration: Not drinking enough water or losing too much fluid (for example, on a hot day) can bring on a migraine. In fact, dehydration is a major headache and migraine trigger for many people​, so staying hydrated is important.
  • Medications: Some drugs can trigger migraines or make them worse. For instance, certain oral contraceptives and vasodilators (like nitroglycerin) have been linked to migraine attacks​.

Not every migraine sufferer has the same triggers, and part of managing migraines is identifying which factors tend to set off your attacks. Often, it’s a combination of factors that together precipitate a migraine.

Symptoms

Visual aura example: a shimmering, zigzag pattern obscuring part of the visual field – an experience reported by some people before a migraine. Migraines are more than just a headache – they are a whole-body experience. Symptoms can vary widely from person to person. A typical migraine attack often progresses through several phases, although not everyone goes through all of them every time​. The common phases and symptoms include:

  • Prodrome (pre-headache phase): Subtle warning signs that can start a day or two before the headache. These may include mood changes (feeling depressed or irritable), food cravings, neck stiffness, frequent yawning, increased urination, or slight fatigue​. Not everyone notices prodrome symptoms, but for those who do, they signal a migraine is coming.
  • Aura (in some migraines): About one in three people with migraine experience an aura, which is a short-term neurological disturbance before or during the headache​. Auras are often visual – you might see bright flashing spots, zigzag lines, or have blurry or tunnel vision. They can also be sensory, such as tingling or “pins and needles” on one side of the face or body, or difficulty speaking​. An aura typically builds up over a few minutes and lasts up to an hour, then usually resolves as the head pain begins. (Many migraine sufferers do not have auras, so lack of aura doesn’t mean it’s not a migraine.)
  • Attack (headache phase): This is the stage of the intense headache pain. Migraine headache pain is often throbbing or pulsing and usually on one side of the head, though it can affect both sides​. Without treatment, an attack can last 4 to 72 hours​. During this phase, there is usually significant disability – the pain may be moderate to severe, and often comes with nausea and sometimes vomiting. There’s often extreme sensitivity to light (photophobia) and sound (phonophobia); sufferers may need to lie down in a dark, quiet room to find relief​. Even routine physical activity like walking or climbing stairs can worsen the pain.
  • Post-drome (after the headache): Once the severe pain subsides, a final phase called post-drome can occur. You might feel drained, fatigued or mentally foggy for a day or so after the headache​. Some people describe feeling “hungover” or washed-out. In some cases, a brief spike of pain can occur with sudden movements during this recovery phase​. On the other hand, a few people report feeling elated or euphoric once the pain is gone – it varies by individual.

Not every migraine follows this exact pattern, but these symptoms are typical. Some migraines are “silent” (aura without a headache), and others might involve additional symptoms like dizziness or sinus pressure. If you experience these symptoms recurrently, it’s likely migraine rather than another type of headache.

Treatments

A combination of medical treatments and healthy habits can significantly help migraine sufferers. There is no single cure for migraines, but there are many effective treatments to reduce symptoms and help you get back to your life. Treatment usually has two goals: relieving symptoms during an attack, and preventing future attacks. Migraine management is very individualized – what works for one person might not work for another – but it often involves a mix of medication and lifestyle measures. Here are some common treatment approaches:

  • Over-the-counter (OTC) medications: For mild to moderate migraines, OTC pain relievers are often the first line of defense. Drugs such as ibuprofen, aspirin, or acetaminophen can be effective, especially if taken early in the attack​. Certain combination medicines specifically marketed for migraines contain acetaminophen, aspirin, and caffeine (the caffeine helps enhance pain relief). These OTC options can often reduce pain if the migraine is caught in the early stages.
  • Prescription medications (acute treatment): When OTC meds aren’t enough, doctors may prescribe stronger drugs for use during a migraine attack. The most common are triptans (e.g. sumatriptan, rizatriptan), which are designed specifically for migraines and can greatly reduce headache pain and other symptoms​. Triptans work best for moderate to severe migraines and are often very effective​. Other acute options include ergotamine derivatives (like dihydroergotamine), anti-nausea medications (to control vomiting and help pain relievers stay down), or newer medications such as CGRP receptor antagonists (ubrogepant, rimegepant) and ditans (lasmiditan). These newer drugs are useful for people who cannot take triptans or who don’t get relief from them. In severe cases, injectable medications or a visit to an urgent care/ER for stronger treatment (like intravenous medicine) might be needed to break a migraine attack.
  • Preventive (prophylactic) medications: If migraines are very frequent or severe, you may need daily medication to prevent attacks. There are several classes of preventive drugs that can reduce the frequency and intensity of migraines. Common first-line preventives include beta-blockers (like propranolol), certain antidepressants (like amitriptyline), and anti-seizure drugs (such as topiramate or valproate)​. These medications are taken daily (or in some cases, before an expected trigger like a menstrual migraine) to make migraines less likely. In recent years, a new class of injectable drugs called CGRP monoclonal antibodies (e.g., erenumab, galcanezumab) has become available for people with frequent migraines – these are given monthly or quarterly and target a protein involved in migraine pathways. The choice of preventive medicine depends on your individual health profile, and it may take a few weeks to months to notice a reduction in headaches.
  • Alternative and complementary therapies: Many migraine sufferers incorporate non-drug approaches into their treatment plan. Techniques like relaxation training, biofeedback (learning to control certain body responses), and cognitive-behavioral therapy can help manage stress and may reduce migraine frequency. Physical treatments such as acupuncture, massage therapy, or chiropractic adjustments have been reported to provide relief for some individuals​. Likewise, mind-body practices like yoga and meditation can help reduce stress and muscle tension, potentially decreasing migraines or making them more tolerable​. Nutritional supplements are sometimes used as well – for example, magnesium, vitamin B2 (riboflavin), or the herbal supplement butterbur (note: consult a doctor before trying supplements). While results vary from person to person, these non-pharmacological therapies can be valuable, especially when combined with medical treatment.
  • Medical procedures: In cases of chronic migraine (15 or more headache days per month), specialized medical interventions might be recommended. One well-known option is Botox injections (onabotulinumtoxinA), which are FDA-approved for chronic migraine prevention. Botox is injected into specific head and neck muscles and can significantly reduce headache frequency in chronic sufferers​. Other procedures under specialist care include nerve blocks (injections of anesthetic around certain nerves) and neuromodulation devices. For example, devices that deliver electrical or magnetic pulses to nerves (such as a vagus nerve stimulator or transcranial magnetic stimulation device) can be used in some cases to either stop a migraine in progress or prevent one. These are usually considered when standard treatments aren’t effective or aren’t well-tolerated.

It’s important for migraine patients to work with their healthcare provider to find the right combination of treatments. Sometimes it takes some trial and error to discover which medications (or what dosages) provide the best relief with the fewest side effects. Never hesitate to discuss with a doctor if your current regimen isn’t working – there are many options available, and new therapies continue to be developed.

Lifestyle Management

While medications can help, lifestyle management is a crucial part of controlling migraines. Making healthy changes and avoiding triggers can reduce how often migraines happen and how bad they get. Here are some practical lifestyle tips for migraine management:

  • Maintain a regular sleep schedule: Aim for a consistent sleep routine with adequate, quality sleep each night. Fatigue and irregular sleep patterns can trigger migraines, so try to go to bed and wake up at the same times each day. Create a restful sleep environment (dark, quiet, and comfortable) to improve sleep quality.
  • Stay hydrated: As mentioned earlier, dehydration can provoke migraines, so drink plenty of fluids throughout the day​. Water is best. Keep a water bottle with you and sip regularly, especially during hot weather or when exercising. Limit excessive caffeine and alcohol, as they can contribute to dehydration (and alcohol itself is a common trigger).
  • Eat a healthy diet and don’t skip meals: Low blood sugar from skipping meals is a known trigger for headaches. Eat balanced meals at regular times. Focus on whole foods – vegetables, fruits, whole grains, lean proteins – and avoid known “trigger foods” that affect you. Common offenders include aged cheeses, processed meats (with preservatives like MSG or nitrates), artificial sweeteners like aspartame, and sometimes chocolate. Not everyone has food triggers, but it helps to notice if certain foods consistently coincide with your migraines and then limit or avoid them.
  • Manage stress: Stress is a big trigger for many, so developing stress-reduction habits is important. Practice relaxation techniques such as deep breathing exercises, meditation, or progressive muscle relaxation. Activities like yoga, tai chi, or gentle exercise can also relieve stress and muscle tension. Taking short breaks during a busy day, and making time for hobbies or anything that helps you unwind, can lower your overall stress levels. If you find your stress is overwhelming, consider talking to a therapist for stress management or cognitive-behavioral strategies tailored to you.
  • Regular exercise: Engage in regular moderate exercise (as your condition allows). Aerobic activities like walking, cycling, or swimming a few times a week can reduce migraine frequency over time. Exercise helps by relieving stress, improving sleep, and releasing endorphins (natural painkillers). Just be mindful not to overexert suddenly, as extremely intense exercise might trigger a headache for some – build up gradually and stay hydrated.
  • Limit caffeine and alcohol: Small amounts of caffeine can sometimes help during a migraine (and caffeine is an ingredient in some migraine medicines), but too much caffeine or daily use can lead to rebound headaches or trigger migraines when you withdraw from it. Try to keep caffeine use moderate and consistent. Alcohol, especially red wine or beer, triggers migraines in many people; if you notice this, avoiding or limiting alcohol is wise.
  • Avoid sensory triggers: If bright light bothers you, wearing sunglasses (even indoors, if necessary, in fluorescent lighting or in front of screens) can help. If loud noise is an issue, consider earplugs or noise-canceling headphones in noisy environments. Strong smells can be hard to control, but you might gently explain to coworkers or family that certain perfumes or odors provoke your migraines, so they understand if you step away or need accommodation.
  • Keep a migraine diary: Tracking your headaches can be very informative. Use a journal or an app to note when each migraine happens, how long it lasts, what you ate or did before it, weather conditions, your stress level, sleep amount, etc. Also record what remedies you used and how effective they were. Over time, patterns may emerge (for example, you get migraines on days you skip lunch, or after a night of poor sleep, or during humid weather). A diary helps you and your doctor identify triggers and evaluate which treatments are working.
  • Build a migraine “toolkit”: Have a plan for when you feel a migraine coming. This might include carrying your medications with you (so you can take them as early as possible), having instant ice packs or a cold compress ready (cooling your forehead or neck can reduce pain), and knowing a quiet, dark place you can retreat to if needed. Some people also find relief with techniques like a gentle neck massage, a warm shower, or practicing deep breathing in a dark room. Find what little comforts help you, and be prepared to use them when an attack starts.

By adopting these lifestyle habits, many migraine sufferers see a decrease in the frequency or severity of their headaches. It essentially raises your threshold for getting a migraine – meaning it might take a larger trigger or more combined factors to set off an attack. Even when migraines do occur, a healthy lifestyle can make you more resilient and aid recovery. Remember that consistency is key: these changes have the best effect when they’re part of your daily routine, not just occasional.

When to Seek Medical Help

Migraines, especially if you’ve had them for years, can sometimes be managed at home with the strategies above. However, it’s important to know when a headache might be something more serious or when you could benefit from professional help. Seek medical attention (contact your doctor or go to an emergency room) if you experience:

  • A sudden, extremely severe headache – often described as a “thunderclap” headache, which peaks within seconds or minutes and is the worst headache of your life. This kind of abrupt, explosive pain can be a sign of a serious issue (like bleeding in the brain) and needs immediate evaluation.
  • Headache with alarming symptoms – if your headache comes with fever, stiff neck, confusion, seizures, or weakness/numbness in part of your body, or trouble speaking/seeing clearly, seek help right away​. These could indicate a stroke or meningitis or another urgent condition, not a typical migraine.
  • Headache after a head injury – if you recently hit your head (for example, in a fall or accident) and then develop a headache, see a doctor​. It could be a concussion or bleeding. Even if you regularly get migraines, don’t just assume a post-injury headache is “another migraine.”
  • A change in your typical migraine pattern – for instance, if your migraines suddenly become much more frequent, significantly more intense, or different in character than before, get a medical evaluation. Also, if you’re over 50 years old and start getting new headaches, it’s wise to see a doctor to rule out other causes​(migraines usually begin earlier in life, so new headaches at an older age need checking).
  • Very frequent or unmanageable migraines – if you find that you’re having migraines on more days than not, or you’re needing to take pain medication more than a couple of times a week, talk to your healthcare provider. You might benefit from preventive treatment or a reassessment of your current plan​. In general, more than about 4 migraine days a month or any migraines that routinely interfere with your ability to function merit a discussion about better management.
  • Migraine that is not responding to your usual treatment – if you’ve taken your prescribed medication and tried your normal relief measures but the headache remains severe or lasts unusually long, it’s time to seek help. There may be stronger treatments a doctor can provide in a clinic or ER setting to break the cycle.

Always err on the side of caution: if you’re unsure whether your headache is a migraine or something more serious, or if something just feels different about it, get medical advice. It’s better to have a doctor tell you everything looks fine than to miss a warning sign of a serious problem. Also, if migraines are affecting your quality of life, don’t hesitate to consult a headache specialist (neurologist) for expert guidance. They can confirm the diagnosis (since other conditions can mimic migraines) and help tailor a treatment plan for you.

Conclusion

Migraines can be challenging and life-disrupting, but the good news is that they can be managed. By understanding your triggers, keeping a healthy lifestyle, and using the right treatments (medications or therapies), you can significantly reduce the impact migraines have on your daily life. It often takes a proactive approach – for example, taking medicine at the first sign of an attack, sticking to routines that promote wellness, and avoiding known triggers – to stay one step ahead of migraines.

Remember that you’re not alone: migraines are a common medical condition, and there are specialists and support resources dedicated to helping people who suffer from them. If you struggle with frequent or severe migraines, work with a healthcare provider to develop a personalized management plan. With the appropriate care and self-management strategies, many people find their migraines become less frequent, less severe, and more predictable. In turn, this means getting back control – being able to plan, to work, to enjoy activities – without always fearing the next migraine.

Empower yourself with knowledge and don’t hesitate to seek help when you need it. While migraines may not disappear completely, every step you take to understand and manage them is a step toward a better quality of life. Here’s to fewer headache days and more of the pain-free, productive days you deserve!

Dr. Raja Radhika Raman
NEUROSURGERY
Meet The Doctor

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